2-Vinylpyridine in Pharmaceuticals
2-Vinylpyridine is the key intermediate in the production of the API, Betahistine, an anti-vertigo medicine.
2-Vinylpyridine is a reactive monomer and once polymerized, the nitrogen is less exposed/accessible than its counterpart, 4-Vinylpyridine. It can be copolymerized with many other monomers, in particular cationic monomers, such as acrylamide, acrylates, and also with other vinyl-based monomers (e.g. styrene). The benefit of the addition of a 6-membered heterocyclic moiety is the increased Van der Waals forces which impart better electrostatic forces to the finished polymer, improving adhesion.
Vinylpyridines provide a unique set of properties to wide range of applications due to good thermal stability, chemical stability, mild basicity, mild pH trigger, and compatibility with most polymerization techniques.
Key Intermediate in Pharmaceuticals
2-Vinylpyridine is the key intermediate in the production of the API, Betahistine, an anti-vertigo medicine. Betahistine is commonly prescribed for balance disorders and helps to alleviate symptoms of vertigo.
Melt Point (°C)
Values shown in the above table are typical properties.
Intermediate in the production of Active Pharmaceutical Ingredients
Artifical Food Dye
Used to provide color to otherwise colorless food
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