Citroflex™ B-6 Plasticizer


When it comes to plastics for medical devices, softness, flexibility, and patient safety are the key attributes. Whether ensuring optimum patient comfort for the tubing that interacts with the body or providing safe storage and transportation of blood and its components, plasticizers play a crucial role.

Vertellus Citroflex B-6 phthalate-free plasticizer offers excellent performance in medical PVC plastics formulations. With a clean toxicological profile, Citroflex B-6 presents a proven, field-tested alternative to traditional DEHP plasticizers.

As an easy, drop-in replacement for DEHP, Citroflex B-6 assures PVC compounders of production continuity with minimal formulation or process adjustment. This empowers compounders to provide blood bag manufacturers with regulatory-compliant products having similar or improved performance.

Medical Components

Citroflex B-6 Plasticizer has low extractability into lipid media, making it particularly useful for blood bags and related products. It nearly duplicates the properties of diethylhexyl phthalate (DEHP).

Medical Tubing

B-6 enables the tubing to maintain flexibility and resistance to cracking at low temperatures. Unlike other phthalate-free alternatives, such as di(2-Ethylhexyl)adipate (DEHA), Citroflex B-6 Plasticizer exhibits lower volatility and reduced potential for leaching. 


Typical Properties

Acid Value
Hydroxyl Value
Saponification Value
Iodine Value
Melt Point (°C)
Specific Gravity

Excellent Alternative to DEHP

PVC films plasticized with Citroflex B-6 demonstrate the following benefits as compared to those plasticized with DEHP:

•  Similar or slightly improved physical properties
•  Reduced brittle point temperature
•  Significantly less volatile loss
•  Lower soapy water extraction

A Phthalate-free Solution, for Flexible PVC Blood Storage and Transfusion Systems

Application Highlights

Blood Bags

High molecular weight,
low extractability,
prevents plasticizer migration

Medical Tubing

Strong polymer compatibility, 
low-temperature flexibility

Additional Resources

Available upon request. Please use the Contact Us form. 

Available upon request. Please use the Contact Us form. 

  • Citroflex™ A-6 Plasticizer

Citroflex™ B-6 Plasticizer

Citroflex B-6 Plasticizer (n-Butyryl Tri-n-hexyl Citrate) is a citric acid ester specially formulated for use in PVC medical articles such as tubing and intravenous bags where the content medium is aqueous-based. 

 Medical application examples include:

  • Extra-corporeal tubing
  • Blood bags
  • IV solution containers & sets
  • Catheters

Citroflex™ Citric Acid Esters

Citroflex citric acid esters are suitable for use as phthalate-free alternatives to plasticizers such as low molecular weight adipates, phthalates, and sebacates in various polymer applications. 

These esters are partially derived from bio-based raw materials and have been demonstrated to be biodegraded by microorganisms in soil.

They are ideal for use in bio-polymer systems and applications where high bio-sourced content or end-of-life biodegradability are desirable.

Citroflex esters are not volatile organic compounds (VOCs).

Versatile. Renewable. Biodegradable.  

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